Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...

Modified, autologous T-cell immunotherapies have been transformative in the treatment of hematologic malignancies with several approvals of chimeric antigen receptor ...

In this issue of JCO Oncology Practice, Majhail et al 1 describe their organization's experience with outpatient chimeric antigen receptor T-cell (CAR-T) cell therapy using a remote patient monitoring ...

A cluster of recent studies has sharpened the scientific picture of how T cells switch on, tracking the molecular signals ...

The standard procedure involves extracting a patient’s T cells, genetically modifying them in specialised facilities to recognise cancer cells, and reinfusing them into the bloodstream. While ...

Professor Gordon Cook says careful patient selection is needed with CAR-T cell therapy, noting its potential in a disease ...

Tumour reactive T cells identified through transcriptional profiling predict response to multiple myeloma immunotherapy and ...

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor ...

MARCH 18, 2026, NEW YORK - The immune system's killer T cells do a commendable job of detecting and destroying cancer cells.