Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers identify the anterior insula as the brain region responsible for biasing decisions toward alcohol over social rewards in addiction.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one ...

The impact of addiction on the brain is both catastrophic and comprehensive. When the brain is damaged by an addicting chemical, its executive functions—including judgment, decision making, and ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Consider someone addicted to alcohol, drugs, or a behavior like gambling. Why do they continue, even when they say they want to stop? It's a question that highlights a fundamental disconnect: the gap ...

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge. The study, published today in ...

Prescription weight loss drugs have been lauded as the miracle drug for treating diabetes and obesity, but new research suggests that these drugs, known as glucagon-like peptide-1 (GLP-1) ...