Existing bacteria and archaea still our universal common ancestor’s ribosomal hibernation defense mechanism when nutrients ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

Ribonucleotide reductases (RNR) are indispensable enzymes that convert ribonucleotides to deoxyribonucleotides (dNTPs), the precursors to make up DNA. Because DNA synthesis is fundamental to cell ...

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, ...

Ribonucleotide reductases (RNR) are indispensable enzymes that convert ribonucleotides to deoxyribonucleotides (dNTPs), the precursors to make up DNA. Because DNA synthesis is fundamental to cell ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions. A ...