Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's ...

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ossificans progressiva (FOP), Mrep functions as a pathogenic cell that ...

A multidisciplinary research team has developed a technique to replicate bone tissue complexity and bone-remodeling processes. This breakthrough could help researchers further their study of bone ...

A multidisciplinary team of researchers at the University of Massachusetts Amherst's Institute for Applied Life Sciences (IALS) have developed a technique to replicate bone tissue complexity and bone ...

A cube of healthy bone is anything but solid. Inside it, countless tiny channels carry fluid and help cells move, feed, and rebuild.

Inspired by how bones heal naturally, researchers have engineered a laser-structured hydrogel that could one day replace conventional bone implants.

Bones broken in a skiing accident usually heal on their own. But if the break is too severe or a bone tumor needs to be removed, surgeons insert an implant that enables the bone to grow back together.