At 17, he started his long journey through addiction treatment units. Now 22, he has been treated numerous times in the ...

Make no mistake, addiction is a neurological brain disorder. When the subject of addiction comes up, people often lean on familiar explanations. “They just need more willpower.” “Why can’t they stop ...

Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

Alcohol addiction, also known as alcohol use disorder, is a serious problem that affects millions of people around the world.

To explore these neural differences, the researchers used a computational approach called “network control theory” to measure how the brain transitions between different patterns of activity during ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

The roots of addiction risk may lie in how young brains function long before substance use begins, according to a new study from Weill Cornell Medicine. The investigators found that children with a ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific “anti-reward” brain circuit becomes hyperactive during withdrawal—driving ...

“I don’t understand why he just can’t stop abusing alcohol.” Turns out that addiction is a whole lot more complicated than just saying “no.” Although the stigma of addiction as a moral failing ...

A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as well as possible treatment options.