Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off ...

As our understanding of the neurobiology of addiction evolves, so do opportunities to develop more precise, brain-based interventions for co-occurring disorders. In our free webinar, “Advancing ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Health Affairs' Rob Lott interviews Nora Volkow, director of the National Institute on Drug Abuse (NIDA) at the National Institutes of Health, to discuss addiction as a brain disorder, treatments for ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.

Playing video games may seem like a harmless way to unwind after a long day at work or school. However, gameplay can sometimes dip into something deeper and more consuming. As gaming technology has ...

“I don’t understand why he just can’t stop abusing alcohol.” Turns out that addiction is a whole lot more complicated than just saying “no.” Although the stigma of addiction as a moral failing ...