该研究成功从人类肠道噬菌体中，发现了一大批能够抑制II型CRISPR系统的Acr，并揭示了一类全新的、结构高度相似却机制多样的抗CRISPR蛋白家族—GutAcraca 噬菌体编码不同的抗CRISPR (Acr)蛋白来对抗细菌CRISPR-Cas系统 ...

Bacterial immune systems protect against viral invaders called phages by precisely targeting specific phage genetic sequences ...

Bacteria get invaded by viruses called phages. Scientists are studying how bacteria use CRISPR to defend themselves from phages, which will inform new phage-based treatments for bacterial infections ...

Researchers identified hundreds of anti-CRISPR proteins in human gut phages, including a new dual-function family that blocks ...

An unexpected find has enabled important progress to be made in the battle against harmful bacteria. An international team of researchers, led by Professor Peter Fineran from the University of Otago, ...

It acts as a sort of molecular fumigator to battle phages and plasmids. CRISPR-Cas9 has long been likened to a kind of genetic scissors, thanks to its ability to snip out any desired section of DNA ...

Overuse of antibiotics has accelerated the emergence of antimicrobial-resistant (AMR) bacterial species. The World Health Organization named antibacterial resistance as a top public health threat to ...

Bacteria combat phage infection using antiphage systems and many systems generate nucleotide-derived second messengers upon infection that activate effector proteins to mediate immunity. Phages ...

Cat1 monomers seen here in shades of pink and purple, while cA4 glueing the dimers to extend the filament are in orange. Every living creature on Earth needs to protect itself from things that would ...

Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, derived from the Greek word for bacteria-eaters, or in shortened form, "phages." Scientists ...