The mechanism by which breast cancer is formed in the cells of mammalian epithelium has been discovered. Although roughly 20 mutations accumulate annually in each epithelial cell until menopause, the ...

Researchers have discovered the key role of the extracellular environment in dictating the ability of mutated cells to induce cancer formation. To form a cancer, cells need to accumulate oncogenic ...

Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion ...

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers. The ...

Chronic inflammation in the gut does more than cause pain and discomfort for people with inflammatory bowel disease. A ...

The field of cancer immunology has undergone significant transformation over the past decade, reshaping our understanding of tumor–immune system ...

Cancer therapies have come a long way since researchers designed the first radiation and chemotherapy treatments. 1 In the past, most cancer researchers focused on finding a single cure for cancer.

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan ...

I still recall my disappointment one day in 2015. I received the tumor DNA sequencing results for one of my patients, whose cancer had spread from her lungs to her brain. I saw not a single genetic ...