Many cancers can often be treated successfully when detected early. Surgery, radiation and chemotherapy are all powerful tools to remove or destroy tumors in their original location. However, when ...

Breast cancer, particularly triple-negative breast cancer (TNBC), remains a leading cause of cancer-related mortality due to its aggressive nature and limited therapeutic targets. Metabolic ...

Building on an in vivo genetic screen in mice to identify host regulators of cancer metastasis, 4 Yang et al. focused on ARHGEF1, which is 1 of 15 genes whose disruption in host tissues decreases the ...

Breast cancer can spread—or metastasize—to many different parts of the body, but it's not well understood why tumors grow better in some organs than others. In a study titled "Nutrient requirements of ...

Metastasis research, including this example from the Karuna Ganesh Lab at MSK, is helping to make progress against cancer's ability to spread. There’s good news about surviving stage 4 cancer — ...