T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

A new cellular atlas charts, in unprecedented detail, how human B cells are built step by step — and offers a window into how this developmental process goes awry in leukemia. The KAUST-led ...

The key for optimizing cell-line development for antibody derivatives might just be to prioritize early assessment of product ...

Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Growing cells in three dimensions is critical for studying how tissues behave in the body, yet most laboratory platforms remain either too simple or too complex to use widely. Researchers now present ...