Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

New findings shed light on how chromosomes manage the various pushing and pulling forces generated when cells divide. Specifically, researchers show that chromosomes resist being punctured by the ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...

This important study demonstrates that a peri-nuclear actomyosin network, present in some types of human cells, facilitates kinetochore-spindle attachment of chromosomes in unfavorable locations - ...

Researchers from the Gerlich Group at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – discovered a molecular mechanism that confers special physical properties to ...

Centromeres play virtually the same central role across the entire tree of life: They ensure the faithful segregation of chromosomes during cell division. Yet the striking diversity in centromere ...

During cell division, chromosomes are duplicated and separated so that one copy of each chromosome is inherited by each of the two emerging daughter cells. Correct distribution of chromosomes requires ...

Some cells can turn cancerous when they divide, due to chromosomes getting “lost” in the process. In a new study, researchers at the University of Warwick have uncovered what happens to these lost ...

Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...