A recent review by Carlo Maley, a researcher at Arizona State University, and Lucie Laplane from the University of Paris Pantheon-Sorbonne critiques the dominant theory of cancer evolution. The ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted ...

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...

In a study published in Developmental Cell, a team led by Prof. Robert K. Naumann from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences (CAS), and researchers from BGI ...

Researchers at Moffitt Cancer Center have developed a new tool to predict how cancer cells evolve. By focusing on chromosome ...

New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Germinal centers are high-speed evolution ...

Cancer cells are driven by the same imperative guiding all living things: to grow, survive and reproduce. Although cancer's evolutionary underpinnings have been recognized since the 1950s, clinicians ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted ...