The cerebellum is instrumental in coordinating movement and refining motor control through intricate neuronal circuitry, with Purkinje cells serving as the central integrators of sensory inputs and ...

Pinpointing the stressors that help trigger or accelerate replicative senescence has proven difficult. Now, in a study ...

Short-term IF boosts glucose homeostasis, but prolonged fasting in adolescence may impair β cell maturation—potentially linking chronic IF to type 1 diabetes risk. Study: Chronic intermittent fasting ...

Jeffrey Moore lab studies how the microtubule network organizes the contents within cells and how problems can cause diseases ...

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the ...

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the ...

Ceramide buildup due to faulty transport triggers stress responses that lock cells into senescence, revealing a potential ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

Aging does not arrive all at once. It builds quietly across years, touching cells long before symptoms appear.

Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

While each method has its pros and cons, a joint study found that LC-MS provides a clearer, more comprehensive picture of the ...