*仅供医学专业人士阅读参考众所周知,T细胞通过主要组织相容性复合体(MHC)识别靶细胞。一直以来,我们都认为,所有细胞表面都存在的MHC-I类分子,仅调节CD8阳性T细胞和NK细胞介导的免疫反应;而只存在于抗原呈递细胞表面的MHC-II类分子,则调节 ...
The article, titled "Emerging roles of immune cell-derived neurotransmitters in immunity and disease," published on March 17, ...
In a paradigm-breaking study, researchers have discovered a novel way the immune system, specifically T cells, attack their ...
Researchers reveal that CD4+ T cells can kill cancer cells lacking MHC I by triggering ferroptosis, challenging established ...
In a paradigm breaking study, Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S ...
Antigen presenting cells capture tumour antigen within the tumour microenvironment and migrate to tumour-draining lymph nodes where they prime tumour-reactive T cells. Tumour-reactive T cells then ...
Immune checkpoint inhibitors have reshaped cancer treatment over the past decade, but the same immune activation that shrinks tumors can also turn against healthy tissue, including the brain. A ...
Immunity is orchestrated by two responses referred to as the innate and adaptive immune systems. Each system works to ...
A collaborative effort led by Professor Wanli Liu 's team at Tsinghua University has uncovered a sophisticated mechanism by ...