Programmable recombinases let one cell produce multiple fates in preset ratios, enabling controlled division of labor, ...

近日，重庆医科大学附属第一医院神经内科肖飞教授团队在国际权威学术期刊 Cell Death & Differentiation《细胞死亡与分化》（IF=15.4，中国科学院/中信所/JCR分区：1区）发表论文 “Crotonylation of STXBP1 exacerbates seizure susceptibility by impairing GABAergic synaptic tra ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...

MIAMI, FLORIDA (AUG. 7, 2025) – Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing ...

A comprehensive map of aberrant hematopoiesis in people with acute myeloid leukemia defines specific cell states and potential therapeutic targets. The team used their reference map for normal ...

As cell therapy advances toward clinical reality, iPSC-derived cellular products, in vivo reprogramming strategies, and ...

There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...