The ESCRT-III complex constitutes a central membrane-remodelling machine that shapes and severs lipid bilayers from the cytosolic face. It assembles as filaments of charged multivesicular body protein ...

Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Researchers at UC Merced used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging. Department of Molecular and Cell ...

Gene regulation in our cells—the decision on which proteins are produced for the various processes of the cell—is strictly regulated. It has long been assumed that this regulation deteriorates with ...

To study biological processes, scientists often take snapshots of the molecules in cells, such as proteins and nucleotides, at specific points in time. In spatial biology, they can leverage molecular ...

Dopamine is a key neurotransmitter known to modulate motivation and reinforcement learning. While the role of dopamine in these reward-related processes is well-established, the cellular and neural ...

Most cancer deaths are caused not by the initial tumor but by the spread of cancer cells to distant organs in the process ...

Cyanobacteria, an ancient lineage of bacteria that perform photosynthesis, have been found to regulate their genes using the same physics principle used in AM radio transmission. Cyanobacteria, an ...

Deep in our cells, a wide range of processes are occurring constantly. These cellular processes rely on enzymes to act as catalysts and set off a series of molecular interactions. There are still many ...

A molecular geneticist at Montana State University has discovered a cellular process once believed impossible by scientists – the creation of the amino acid cysteine within a living cell when the cell ...

Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department ...

A buildup of a structural protein called F-actin inside aging brain cells appears to cripple the cellular waste-clearing machinery that keeps neurons healthy, according to a study in Drosophila fruit ...