Caenorhabditis elegans has emerged as a robust model for dissecting the fundamental mechanisms of innate immunity and host–pathogen interactions. Despite lacking an adaptive immune system, C. elegans ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Pathogens are ubiquitous and a constant threat to their hosts, which has led to the evolution of sophisticated immune systems in bacteria, archaea and eukaryotes. Bacterial immune systems encode an ...

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American The very first line of defence against any ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital published today in ...

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

Phospholipases PLA1, PLA2, PLC, and PLD hydrolyze phospholipids to produce corresponding lysophospholipids and fatty acids. Red arrows indicate the corresponding hydrolysis sites. B) Phospholipases ...

SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses. The discovery may ...

Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated ...