Three the approved drugs for Alzheimer’s disease attempt to boost the brain’s supply of acetylcholine, a critical neurotransmitter for cognition that wanes in people with the disease. But might ...

Key components of the non-neuronal cholinergic system (NNCS) including nAChRα7 are strongly expressed in macrophages. The NNCS regulates phagocytosis in macrophages via multiple signaling pathways ...

Acetylcholine "conductors" in the striatum directly trigger serotonin release, offering new insights into the origins of OCD and chemical imbalances.

Scientists have found that that activation of cholinergic neurons -- those that release the neurotransmitter acetylcholine -- in two brain stem structures can induce REM sleep in an animal model.

Scientists have uncovered a powerful strategy that the brain uses to coordinate chemical signaling. In a new study, researchers found that in the striatum, a brain region central to learning and ...

Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated. Several single ...