Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

Some of the signs of aging in human cells originate in the cell nucleus, because the packaged form of DNA changes with age.

Chromatin's structure plays an important regulatory role in DNA template-dependent processes including transcription, replication, recombination, repair, segregation, chromosomal stability, cell cycle ...

The way the body ages could be more resilient than previously thought, a new study suggests. Published in the Journal of the American Chemical Society, the work by researchers at King's College London ...

Chromatin bridges are strands of incompletely segregated DNA connecting the anaphase poles or daughter nuclei. If unresolved, chromatin bridges can break in cytokinesis leading to micronuclei ...

Chromatin bridges are DNA strings that link anaphase poles or daughter nuclei and are associated with carcinogenesis. In response to chromatin bridges, mammalian cells delay abscission by activating ...

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...