Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...
Chromatography is an analytical technique used to separate and detect the chemical components in a sample. It is an incredibly versatile technique that can be used in essentially any scientific ...
Process characterization and viral clearance validation are pivotal studies in biopharmaceutical manufacturing, particularly for monoclonal antibodies (mAbs) produced in mammalian systems, which carry ...
Purification by affinity chromatography on immobilized calmodulin is suitable for recombinant proteins expressed in bacteria because endogenous bacterial calmodulin-binding proteins are unknown.
Development of robust purification processes requires significant time and resources. In addition, steadily increasing demands from regulatory authorities for better understanding and control of ...
There is a growing demand for high purity chemicals within the technical, life science and fine chemical industries. As new synthetic routes are discovered and purity requirements increase, the demand ...
What is 2D liquid chromatography? Two-dimensional (2D) liquid chromatography is a powerful tool to separate complex compound mixtures. The principle behind 2D liquid chromatography is that compounds ...
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