Animal karyotypes display a great diversity in number and morphology. Mammalian genomes can be resolved by chromosome painting into comparatively large conserved chromosomal segments. Rearrangement of ...

We have performed haplotype analysis at the Chronic DSMA locus in a series of 12 European families. Using a homozygosity mapping strategy, we mapped the Chronic DSMA locus to a short genetic interval ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...