Previous studies have suggested that austocystin D is oxidized by cytochrome P450 (CYP) oxygenases which then induces DNA damage and suppresses cell proliferation. In this study, we showed that CYP2J2 ...

The detrimental effects caused by substances or environmental changes on cell health are described as cytotoxicity. When cells are exposed to a cytotoxic stimulus, their metabolic activity may be ...

Universal solid tumor therapy with CD5-deleted, DSG2-directed CAR-T cells. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.

Advanced 3D spheroid models are being widely acknowledged as a vital tool for better evaluation of cancer immunotherapy agents in-vitro. This article describes the potential to kinetically visualize ...