What causes gray matter loss in Multiple Sclerosis? New research identifies DNA damage in CUX2 neurons as a primary driver of MS progression.

Multiple sclerosis kills neurons in the cortex, along with destroying the brain's wiring. Now we know how this happens.

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

Paras Gaur, a postdoctoral researcher at the University of Iowa, investigates DNA damage repair and G-quadruplex structures ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a second, equally critical function, safeguarding the integrity of human DNA.

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by researchers at Goethe University Frankfurt, part of the Rhine-Main University ...