Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one ...

Last April, neuroscientist Sue Grigson received an e-mail from a man detailing his years-long struggle to kick addiction — first to opioids, and then to the very medication meant to help him quit. The ...

Despite fewer new addiction cases worldwide, a sweeping analysis finds drug-related deaths surging, exposing critical failures in global harm-reduction and recovery systems. Study: The evolving burden ...

Nick Padlo’s addiction to alcohol and drugs didn’t happen overnight. “I was using them as a tool to cope with depression and anxiety,” says the recovered addict and founder of Sophros Recovery in ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...