Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine stand out as the most dangerous.

Rutgers‑led study of 2.2 million people finds addiction risk is driven more by genes tied to impulse control and reward ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

There’s growing evidence that GLP-1 drugs can treat more than diabetes and obesity. “It was a surprise to people. Here’s an ...

GLP-1 drugs like Ozempic have long helped people eat less — now, they’re showing promise in helping people crave less. A new ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

A popular class of drugs for treating diabetes and obesity reduces addiction, including abuse of alcohol, tobacco, cannabis, ...

Prescription weight loss drugs have been lauded as the miracle drug for treating diabetes and obesity, but new research suggests that these drugs, known as glucagon-like peptide-1 (GLP-1) ...