Jacob Berlin, PhD, CEO of Terray Therapeutics, explains that the critical element to “get right” for a preclinical drug discovery campaign is identifying molecules that rank best among the candidate ...

BUFFALO, N.Y. — One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs). These small molecule drugs form covalent ...

PASCO COUNTY, Fla. (WFL) – The Pasco County Sheriff’s Office warned parents Tuesday about a dangerous drug. Deputies said the drug, carfentanil, has “incredible potency.” “Carfentanil is causing an ...

Researchers at Baylor College of Medicine have developed a powerful new data analysis method named COOKIE-Pro (Covalent Occupancy Kinetic Enrichment via Proteomics) that provides a comprehensive, ...

Human cancer cells cultures in the lab of David Heppner. Heppner's team recently found that faster binding for targeted covalent inhibitor drugs was linked to greater potency, but only to a certain ...

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs). These small molecule drugs form covalent bonds with their ...

Abzena, a CDMO, said it has expanded its early- and late-phase analytical capabilities to now include GMP cell-based potency assays at their Cambridge, U.K., and San Diego, CA, development and ...

"AI-driven binding affinity prediction has evolved from a niche method to a core component of modern drug discovery workflows. SandboxAQ is proud to deliver this powerful capability to the consortium ...