Early, goal-directed therapy did not improve outcomes or reduce death risk for septic shock patients, according to a study published in The New England Journal of Medicine. Researchers conducted a ...
This well-conducted, preplanned, patient-level meta-analysis again demonstrates that use of EGDT in sepsis does not improve clinical outcomes compared with contemporary sepsis care where methods are ...
Background After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ...
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