Researchers show small molecules that alter RNA structure have greater functional impact than those that only bind, offering ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

The field of RNA-targeted therapeutics is rapidly evolving, offering groundbreaking opportunities for the treatment of a wide array of diseases ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

Researchers from A*STAR’s Genome Institute of Singapore (GIS) have found an innovative approach to sequencing single-cell ribonucleic acid (RNA) to study the roles of RNA structure in individual cells ...

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA—a single-stranded molecule similar in many ways to DNA—like some modern viruses. This is because, like ...

RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department ...

During a session hosted by the Division of Biochemistry and Chemical Biology (BIOL), Wei Sun, a chemical biologist at ...

The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...

An artistic representation of the temperature dependence of the RNA free-energy landscape (FEL) of folding. The authors showed that RNAs undergo a phase transition in the cold and misfold due to the ...