A key fusion protein keeps developmental programs active in brain cells, preventing maturation, and fueling tumor growth, ...

The Food and Drug Administration (FDA) has granted Fast Track designation to TRI-611 for the treatment of anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer (NSCLC).

A single genetic abnormality found in more than two-thirds of supratentorial ependymomas, a deadly class of pediatric brain tumors, does far more than activate one inflammatory pathway. The ZFTA-RELA ...

BUFFALO, N.Y., — Many childhood cancers start with a hijacking at the molecular level. A group of abnormal proteins known as fusion proteins aberrantly engage with a collection of proteins that ...

TRIANA Biomedicines, Inc. (TRIANA), a leading biopharmaceutical company focused on advancing a target-first and proximity-first molecular glue discovery platform to address difficult to drug disease ...

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists to ...

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists to ...

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and ...

"Emerging Fusion Protein Technologies Drive Innovation in Targeted Therapies Across Autoimmune, Cancer, Metabolic, and Cardiovascular Diseases" Boston, Dec. 11, 2025 (GLOBE NEWSWIRE) -- According to ...

Research originally authored by Kanvasri Jonnalgadda, Lam R. Markely, Scott Estes, Shashi Prajapati at High-Throughput Analytical Group (HTAG)-Cell Culture Development, Biogen IDEC, Cambridge, and MA ...