Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, ...

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries ...

Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in ...

What do your genes have to do with growing old? Quite a lot. But is it due to the actual DNA, or the way those genes are expressed? KPBS sci-tech reporter Thomas Fudge has more on new research that ...

For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer's disease, their ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

How does APOE4 cause Alzheimer's? A new study identifies the Nell2 protein as the driver of neuron shrinkage and brain ...