这届精子「不行」了，已是许多研究的共识。 与 50 年前相比，男性精子浓度下降了约 51.6%，精子总数下降了约 62.3%，且 2000 年后的下降趋势愈发显著。（点击查看丁香园往期报道：） 为了拯救「不行」的精子，科学家们也做出了许多努力。 最近 Science上就发表了一篇研究，研究者从胚胎干细胞开始，在体外培养出了睾丸组织，而且这种睾丸组织，还能为生殖细胞的发育提供有效的环境。[1] 不论 ...

Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors Clinical trials frequently include ...

Innovations in the care of adolescent and young adult (AYA) germ cell tumors (GCTs) are needed for one of the most common AYA cancers for which treatment has not significantly changed for several ...

Tsukuba, Japan—Animal organs are enclosed by a specialized epithelial layer. Epithelial cells typically exhibit apicobasal polarity: their apical surfaces contact other cells or the environment, ...

Non-seminoma is a type of germ-cell testicular cancer. Treatment may include surgery to remove a testicle, lymph node removal, and chemotherapy. Most cases of testicular cancer develop from germ cells ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...