Researchers have built a series of CRISPR-based platforms that can switch endogenous genes on and, just as critically, dial ...

The Tas protein uses an RNA guide to recognize a specific target DNA sequence. A vast search of natural diversity has led scientists at MIT’s McGovern Institute and the Broad Institute of MIT and ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

Researchers have found that certain bacteria carry a naturally occurring system, built from repurposed CRISPR components, that switches genes on rather than cutting or silencing DNA. The discovery, ...

During a session hosted by the Division of Biochemistry and Chemical Biology (BIOL), Wei Sun, a chemical biologist at ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

A research team from The Hong Kong University of Science and Technology (HKUST) has made an advance in understanding the molecular machinery of RNA silencing. The team uncovered how the human enzyme ...