In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...

Preclinical studies show that engineered heart muscle (EHM) can remuscularize damaged heart tissue, but most evidence comes from small-animal studies, which have limited ability to predict outcomes in ...

New research from a multi-institutional team, published in Nature Cardiovascular Research, reveals that heart failure and atrial fibrillation share underlying genetic and molecular mechanisms, ...

A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...

Elizabeth Cooney is a cardiovascular disease reporter at STAT, covering heart, stroke, and metabolic conditions. You can reach Liz on Signal at LizC.22. By its name and nature, heart failure doesn’t ...

The problem is that mammalian heart muscle cells, known as cardiomyocytes, lose their ability to proliferate shortly after birth. Researchers have long sought to induce these cells to start dividing ...

Study: Engineered heart muscle allografts for heart repair in primates and humans. Image Credit: mi_viri/Shutterstock.com In a study published in Nature, researchers found that a stem cell-derived ...

A broken heart will mend over time. However, this isn’t the case for heart tissue following a heart attack. While skin and many other tissues of the body retain the ability to repair themselves after ...

University of Alabama at Birmingham researchers, led by Jianyi “Jay” Zhang, M.D., Ph.D., and Lei Ye, M.D., Ph.D., generated the human leukocyte antigen-knockout ...

A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...