生物通

靶向治疗肥厚型梗阻性心肌病（HOCM）的新纪元：心肌肌球蛋白抑制剂 ...

本文聚焦肥厚型梗阻性心肌病（HOCM）的精准治疗突破，介绍了心肌肌球蛋白抑制剂Mavacamten（Camzyos°）如何通过靶向抑制过度交联桥形成，持续改善LVOT梗阻、症状及生活质量，堪称“游戏规则改变者”。同时探讨溃疡性直肠炎指南推荐的局部治疗应用不足现状 ...
生物通

靶向心肌肌球蛋白抑制剂Mavacamten为梗阻性肥厚型心肌病（HOCM）提供 ...

本文编辑推荐：针对梗阻性肥厚型心肌病（HOCM）治疗难题，研究者聚焦心肌肌球蛋白抑制剂Mavacamten（Camzyos°）的长期疗效。EXPLORER-HCM研究数据显示，持续治疗3.5年可显著改善左室流出道梗阻（LVOT）和患者生活质量。该靶向疗法已被纳入2023版欧洲心肌病管理指南 ...
腾讯网

山大二院开展国内首批三维系统下房颤脉冲消融手术

近日，山东大学第二医院心血管内科电生理团队完成了国内首批三维系统指导下房颤脉冲消融手术，为一名合并肥厚型梗阻性心肌病（HOCM）的复杂房颤患者解除病痛。 据了解，患者为老年女性，长期受房颤及肥厚型梗阻性心肌病双重疾病困扰，此前曾在外院 ...
EurekAlert!

Heart drug improved exercise tolerance in clinical trial of patients with hypertrophic ...

Exercise intolerance is often severe among patients with cardiovascular disease and can impose significant limitations on their physical abilities and quality of life. Medications known as cardiac ...
The New York Times

She Often Fainted in Hot Weather. What Was Wrong?

The woman, a field geologist, was healthy and active, yet she would pass out at inopportune moments. By Lisa Sanders, M.D. The day was sweltering. The 61-year-old woman urged her donkey into a trot.
Time

How to Talk to Your Family About Their Heart Health History

Klein is a contributor for TIME. Klein is a contributor for TIME. Hypertrophic obstructive cardiomyopathy (HOCM) is the most common genetic heart disease, affecting about 1 in every 500 people, ...
TCTMD

Survival After Septal Ablation for HOCM Similar to General Population

Highly symptomatic patients who undergo alcohol septal ablation (ASA) for hypertrophic obstructive cardiomyopathy (HOCM) have long-term survival rates comparable to those of the general population, ...
Healio

Mavacamten for symptomatic obstructive hypertrophic cardiomyopathy

Please provide your email address to receive an email when new articles are posted on . Hypertrophic cardiomyopathy is the most common genetic heart disease, with prevalence estimates from one in 200 ...