How many photons are in a Green Fluorescent Protein (GFP)? More than you may have thought. The illumination required to excite fluorophores leads to their gradual photodegradation, a phenomenon known ...

After it fills with cargo, the pit pinches off to form a clathrin-coated, membrane-bound vesicle inside the cell, which then proceeds to its proper destination. In cultured cells, hundreds of these ...

Research groups led by Prof. Bi Guoqiang, University of Science and Technology of China (USTC), and Prof. Zhou Pengcheng from Shenzhen Institutes of Advanced Technology of Chinese Academy of Chinese ...

Biophysicists have developed control software that optimizes how fluorescence microscopes collect data on living samples. Their control loop, used to image mitochondrial and bacterial sites of ...

Labs can be resource-intensive areas, but there are many ways we can make a positive change and become more sustainable. There is a growing trend towards sustainability throughout the scientific ...

Imagine you’re a PhD student with a fluorescent microscope and a sample of live bacteria. What’s the best way use these resources to obtain detailed observations of bacterial division from the sample?

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A device that can convert a smartphone or tablet into a fluorescence microscope for less than US $50 is presented in a proof-of-principle study in Scientific Reports. The authors suggest that the ...

Advancing our understanding of the human brain will require new insights into how neural circuitry works in mammals, including laboratory mice. These investigations require monitoring brain activity ...

Chip technology presents a whole different view on microscopy. Chips are compact and can integrate multiple functionalities. The scaling possibilities could allow chip-based microscopes to be produced ...