Organelles spit out DNA contaminated with damaging components, leading to the activation of inflammatory enzymes, mouse experiments show. Scientists found that, in the cells of ageing mice with kidney ...

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and chronic inflammation. A new chemical tool developed at UC Riverside ...

Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...

Aging, neurological diseases and our bodies' stress response are all linked to the tiny power plants inside each cell known as mitochondria. To function properly, mitochondria must first read ...