Guillain-Barré syndrome (GBS) is an acute inflammatory neuropathy that can lead to severe weakness of the limbs, face, and respiratory muscles. Its pathophysiology involves autoantibodies that attack ...

Patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphomas (NHLs) who received frequent tests for immunoglobulin G (IgG) were less likely to experience severe infections compared with ...

The generation of pathogenic autoantibodies is a crucial event in the development of inflammation and complement activation, leading to immune cell responses. These cellular responses cause tissue ...

IdeS IgG protease shows promise for Myasthenia Gravis, Immune Thrombocytopenia, and dozens of other IgG-driven autoimmune diseases. The wild type enzyme elicits potent anti-drug antibodies (ADA) that ...

Neutrophil extracellular traps in relation to efficacy of systemic therapy for metastatic renal cell carcinoma. This is an ASCO Meeting Abstract from the 2024 ASCO Genitourinary Cancers Symposium.

Clinical outcomes and tolerability of ipilimumab/nivolumab in older (≥70 years) versus younger patients with metastatic clear cell RCC: A multi-institutional analysis of 514 patients. This is an ASCO ...