A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a ...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill ...

BUFFALO, N.Y. – The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these ...

Researchers have identified a crucial ion channel, TMEM175, that acts like an overflow valve in the cell’s recycling system.

HHMI researchers discover a new ion channel that is found only in the tails of spermatozoa. An ion channel protein that plays a central role in sperm motility could be an enticing target for a new ...

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine (UCI) ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Maintenance of cardiac rhythm and pain sensation require the flow of ions across the membranes of all cells. Ion channels, which facilitate this movement, are protein assemblies that penetrate the ...

Cartoon of the 3D models of the broad bean (right, pink-violet) and the thale cress (left, blue) TPC1 ion channel protein in the vacuole membrane. On the left, Calcium ions (red spheres) in the ...