As a field, lipidomics is in its infancy, yet it has already begun to influence lipid biochemistry in myriad ways. As with other omic technologies, the field is driven by advances in analytical ...
A widely accepted hypothesis in contemporary cell biology is that freely diffusing, stable, lateral assemblies of sphingolipids and cholesterol, which are termed lipid rafts 1,2,3 constitute an ...
Mutation burden and microsatellite instability in colorectal cancer in Japan and US. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I. This abstract does not include a full text ...
Studying how our bodies metabolize lipids such as fatty acids, triglycerides, and cholesterol can teach us about cardiovascular disease, diabetes, and other health problems, as well as reveal basic ...
Although researchers have been working on lipid biochemistry for many decades, lipidomics is a more recent, newly emerging discipline – with potential applications for diagnosing and preventing ...
We know very well that metabolites—small molecules such as lipids, sugars, nucleotides, and amino acids—play a large role in cellular biochemistry. But we are only beginning to understand the many ...
Membrane proteins spend their time surrounded by lipids. For a long time, researchers thought those lipids didn’t really matter, that they were just a backdrop for the real players, an annoyance to be ...
This project explores how a specific group of lipids, key membrane components and dynamic signaling molecules, shape cellular fate by regulating both senescence and cell death. Project is Not ...
Our bodies are made of cells. Each cell is a soup of smaller components, all working together to execute the body’s various functions. Perhaps the most well-known of these components are proteins — ...
My background is in chemical biology: developing and using chemical tools to help solve intractable problems in biology. I got interested in studying infectious disease after living in Mozambique, ...