A new study reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholesterol that can otherwise cause damage to arteries. The findings suggest that the response to ...

Scientists from Children’s Medical Research Institute (CMRI) have successfully tested adeno-associated viral vector-based (AAV) gene therapies in whole human livers in the lab. The study, which is ...

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead ...

The connection between the human liver and the intestine is unique, and the “gut-liver axis” plays a vital role in regulating liver disease pathology. When homeostasis is disturbed, changes in dietary ...

Artificial liver support systems can simulate some functions of a person’s liver. They can act as a bridge treatment for people with liver diseases until they recover or receive a transplant.

Type 2 diabetes (T2DM) is a systematic multi-organ metabolic disease, which is characterized by dynamic interplay among different organs. Pancreatic islet-liver axis is closely associated with normal ...

Researchers at Cincinnati Children's Hospital Medical Center in collaboration with Roche, have developed a next-generation human liver organoid microarray platform that could help predict which drugs ...

Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF. Despite the many individual successes of transplantation in the United States, key ...