Carboxylesterases are a class of enzymes that play a pivotal role in the metabolism of a wide array of endogenous and exogenous compounds. Predominantly expressed in the liver and intestine, these ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as pivotal players, offering new avenues for understanding the fine-tuned ...

Metabolic syndrome (MetS) is a multifaceted disorder characterized by a constellation of metabolic abnormalities, including central obesity, dyslipidemia, ...

Northwestern Medicine scientists led by Joseph Bass, MD, Ph.D., the Charles F. Kettering Professor of Endocrinology and ...

A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

Age related muscle loss not only affects strength and mobility but also your metabolic health. Dr Manickam shares 5 changes that drive risk.

In fact, metabolic health has come into greater focus recently, as the awareness around and tools for Type 2 diabetes (like GLP-1s) have increased. But metabolic health isn't only about blood sugar.

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

A new study reveals how a simple dietary shift could transform gut health, weight, and heart risk factors in a surprisingly ...

Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features. A polygenic risk score (PRS) can capture multiple genetic risk factors ...