Figure 3: Exon 7–skipping correlates with disruption of the proximal SF2/ASF heptamer motif. Figure 4: The SMN1 SF2/ASF heptamer motif is a bona fide ESE. Figure 5: SF2/ASF promotes inclusion of SMN1 ...

SF2/ASF is a prototypical serine- and arginine-rich protein, with important roles in splicing and other aspects of mRNA metabolism. Splicing factor, arginine/serine-rich 1 (SFRS1), the gene encoding ...