Genetic modification aimed at understanding the function and pathology associated with specific genes is most commonly undertaken in mice, as about 99 percent of human genes have mouse orthologs. 1 ...

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries ...

CRISPR-Cas technology has radically changed how transgenic models are created. Through CRISPR approaches, researchers have pioneered how to create complex animal models, including long cassette ...

A mouse’s entire nervous system lights up in psychedelic hues. Clumps of immune cells attacking tumors give off a ghostly glow. The vessels that make up the body’s sewer system flare brightly. These ...

Two Americans and one Briton -- Mario R. Capecchi, Oliver Smithies, and Sir Martin Evans, respectively -- have won the Nobel Prize in Physiology or Medicine for developing the technology to manipulate ...

This microscope image provided by Xiao-Yang Zhao of the Southern Medical University in Guangzhou, China on Thursday, Feb. 25, 2016, shows rudimentary mouse sperm derived from stem cells. The sperm, ...