Smooth muscle cells use an actin-myosin II-based contractile apparatus to produce force for a variety of physiological functions, including blood pressure regulation and gut peristalsis. The ...

Researchers have described, for the first time, the ordered arrangement of myosin-II filaments in actin cables of non-muscle cells. Researchers from the Mechanobiology Institute, Singapore (MBI) at ...

The team showed with microsecond resolution that the head of myosin first binds weakly to actin. That bond strengthens, however, as myosin moves along the actin filament and finds the position for ...

Osaka, Japan - Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also ...

Actomyosin is a protein complex composed of actin and myosin. It is found in muscle fibers where it plays a role in muscle contraction. Actin is one of the most abundant proteins in eukaryotes. It ...

Nebulin is a giant modular sarcomeric protein that has been proposed to play critical roles in myofibrillogenesis, thin filament length regulation, and muscle contraction. To investigate the ...

Scientists have used the latest advances in microscopy to characterize how a motor protein helps cells crawl, according to a study published in the Journal of Cell Biology.

An electron microscope has been used to capture the first three-dimensional image of a tiny filament, or strand, of an essential muscle that the palm-sized water bug Lethocerus indicus uses to fly.

Researchers from the Mechanobiology Institute, Singapore (MBI) at the National University of Singapore have described, for the first time, the ordered arrangement of myosin-II filaments in actin ...