The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

Researchers identified biallelic variants in RNU2-2 as the cause of a recessive neurodevelopmental disorder marked by ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

This Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing. The human genome is a vast landscape, with less than 2% of its sequence encoding proteins. For many years, ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor ...

Scientists profiling small non-coding RNAs in postmortem brain tissue from people with schizophrenia and bipolar disorder ...

When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified and described a previously unknown ...

Three studies published in Nature Genetics look at the identification of a common recessive neurodevelopmental disorder (NDD).

New Delhi: American developmental biologist Victor R. Ambros and fellow molecular biologist Gary Bruce Ruvkun were awarded the 2024 Nobel Prize in Physiology or Medicine Monday. They won the award for ...