circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...

Long non-coding RNAs exist in the so-called "Wild West" (99%) of the human genome that is currently understudied. Not only does this finding have treatment implications for patients with ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

Researchers from the University of Ottawa’s Faculty of Science have achieved a significant breakthrough in the field of enzymology. Three graduate students, namely Noreen Ahmed, Nadine Ahmed, and ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that recognized ...

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...

Three studies published in Nature Genetics look at the identification of a common recessive neurodevelopmental disorder (NDD).

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

A research team led by scientists at Columbia’s Zuckerman Institute used techniques including single cell genomics, to describe a previously undetected RNA-mediated mechanism in mice that could ...