Endosomal and cytosolic nucleic acid receptors sense microbial nucleic acids and initiate innate immune responses. However, in some circumstances their activation by endogenous nucleic acids can also ...

Nucleic acid extraction is a fundamental step in unlocking the genetic information contained within biological samples. Isolated nucleic acids are the basis for a multitude of analyses and ...

What are spherical nucleic acids (SNAs)? What do they consist of and how do they differ from linear nucleic acids? Spherical nucleic acids are structures that are made by taking a nanoparticle ...

Nucleic acids are chains of nucleotides that are a vital part of all living beings. The two most common types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), which provide ...

Nucleic acids such as DNA and RNA play a central role in gene therapies and vaccines. They store and transmit biological ...

Saliva is a viable alternative source of nucleic acids. A new collection device offers stable and easy saliva collection for extracting both DNA and RNA from a single sample.

Biocompatible silicon nanoneedles, which can efficiently deliver nucleic acids and nanoparticles into biological cells without damaging them, have been developed by an international team of ...

The research focus of the Müller group is the bioinorganic chemistry of nucleic acids with a particular emphasis on the generation, characterization as well as application of nucleic acids including ...

Some biologists have long hoped that small pieces of RNA that silence genes could help wipe out genetic diseases. But developing nucleic acid medications with good drug properties, such as selectivity ...

Quantification of nucleic acid concentrations is often performed by measuring light absorption in UV-VIS spectrometers. There are a few challenges faced in this measurement method. In UV-VIS ...

Understanding the integrity and quantity of your nucleic acid samples is critical for next-generation sequencing (NGS) and biobanking workflows. Whether you are working with gDNA, cfDNA or RNA, this ...