Understanding the delicate balance between nucleophilicity and electrophilicity is fundamental to rationalising reaction mechanisms in organic chemistry. Nucleophilic reactivity describes a molecule’s ...

The research team of Xumu Zhang and Genqiang Chen at Southern University of Science and Technology has achieved a new breakthrough in the synthesis and application of benzoxoxetine ligands. They ...

The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...

Organic chemistry students and bench chemists alike rely on the Grignard reaction, a relatively simple way to make carbon-carbon bonds. But even though the reaction was first described 120 years ago, ...

In introductory organic chemistry courses, students learn about reaction mechanisms, often by drawing neat arrows connecting one intermediate state to the next until ending with a final product.