The Biginelli reaction, first reported over a century ago, represents a robust three‐component condensation strategy to synthesise 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) from accessible substrates ...

Highly reactive organometallic reagents, like organolithiums (molecules with a carbon–lithium bond) are essential reagents in organic synthesis because of their applications from polymer synthesis to ...

Scientists introduce a large language model-based AI system that revolutionizes chemistry by integrating 18 advanced tools for tasks like organic synthesis and drug discovery. EPFL scientists ...

A team has shown that artificial photosynthesis is feasible using organic materials. Using the technique, they successfully synthesized useful organic compounds, including pharmaceutical materials, ...

What are Covalent Organic Frameworks (COFs)? Covalent Organic Frameworks (COFs) are composed of light elements such as oxygen, nitrogen, and carbon, connected by strong covalent bonds, providing ...

Organic chemist Neil A. Garg and his team at the University of California, Los Angeles, love testing the limits of what molecules can do. Their latest paper upends Bredt’s rule, a 100-year-old ...

Coupling reactions are among the most transformative tools in organic chemistry, enabling the formation of crucial chemical bonds in pharmaceuticals, agrochemicals, and advanced materials. Since their ...

A research team led by Prof. Sun Jianwei has achieved an advancement in organic synthesis and medicinal chemistry by ...

Scientists at the EU4MOFs research network have taken the initiative to standardize the reporting of synthetic procedures and material properties of metal–organic frameworks (MOFs). To this aim, they ...

Reactive intermediates, such as carbocations, carbanions, radicals, carbenes, nitrenes, and organometallic species, play a crucial role in organic syntheses, yet their transient nature makes them ...