Ischemia–reperfusion injury caused by vascular clamping contributes to the decline in glomerular filtration rate following partial nephrectomy. Ischemia is the main modifiable factor that determines ...

Partial nephrectomy is performed more frequently for small, incidentally discovered, low-stage renal tumors. Importantly, one should distinguish the imperative indications for such surgery from the ...

Partial nephrectomy has been the procedure of choice for patients with poor renal function, tumors in solitary kidneys or bilateral renal tumors. The efficacy of partial nephrectomy in regard to ...

Absolute indications include circumstances in which RN would render the patient anephric, with a consequent immediate need for renal replacement therapy. Patients with an anatomically or functionally ...

a Mean creatinine after 10 years of follow-up. b Median creatinine after median 24 months of follow-up. NR, not reported. Nephron-sparing surgery (NSS) for renal cell carcinoma has the advantage of ...

Immune checkpoint inhibitors in the peri-operative setting in renal cell carcinoma: A meta-analysis of the randomized clinical trials. Cabozantinib in combination with atezolizumab in non-clear cell ...

A person normally has two kidneys with a million functioning units called nephrons in each kidney. Open partial nephrectomy is a surgical procedure in which a part of a kidney is removed due to either ...

Impact of concomitant medication use on treatment outcomes in patients with RCC treated with immune checkpoint inhibitors. First-in-human phase 0 safety, imaging, pharmacokinetics, and dosimetry study ...

The size of the cancer and whether it has spread will help your surgeon decide what type of surgery you can have. They might recommend you have part of your kidney removed (partial nephrectomy) or ...

Positive surgical margins after partial nephrectomy for RCC independently predict a higher risk for cancer recurrence. Positive surgical margins (PSMs) following partial nephrectomy for renal cell ...

PN and RFA offer similar survival for cT1a RCC tumors ≤2 cm, but PN is superior for larger tumors. RFA may be considered for elderly patients with comorbidities, especially for tumors ≤2 cm. PN ...